diff --git a/beacon_node/store/src/iter.rs b/beacon_node/store/src/iter.rs
index 55c525b11..11969e2a9 100644
--- a/beacon_node/store/src/iter.rs
+++ b/beacon_node/store/src/iter.rs
@@ -305,7 +305,7 @@ mod test {
         state_a.slot = Slot::from(slots_per_historical_root);
         state_b.slot = Slot::from(slots_per_historical_root * 2);
 
-        let mut hashes = (0..).into_iter().map(|i| Hash256::from(i));
+        let mut hashes = (0..).into_iter().map(|i| Hash256::from_low_u64_be(i));
 
         for root in &mut state_a.block_roots[..] {
             *root = hashes.next().unwrap()
@@ -333,7 +333,7 @@ mod test {
         assert_eq!(collected.len(), expected_len);
 
         for i in 0..expected_len {
-            assert_eq!(collected[i].0, Hash256::from(i as u64));
+            assert_eq!(collected[i].0, Hash256::from_low_u64_be(i as u64));
         }
     }
 
@@ -348,7 +348,7 @@ mod test {
         state_a.slot = Slot::from(slots_per_historical_root);
         state_b.slot = Slot::from(slots_per_historical_root * 2);
 
-        let mut hashes = (0..).into_iter().map(|i| Hash256::from(i));
+        let mut hashes = (0..).into_iter().map(|i| Hash256::from_low_u64_be(i));
 
         for root in &mut state_a.block_roots[..] {
             *root = hashes.next().unwrap()
@@ -376,7 +376,7 @@ mod test {
         assert_eq!(collected.len(), expected_len);
 
         for i in 0..expected_len {
-            assert_eq!(collected[i].0, Hash256::from(i as u64));
+            assert_eq!(collected[i].0, Hash256::from_low_u64_be(i as u64));
         }
     }
 
@@ -391,7 +391,7 @@ mod test {
         state_a.slot = Slot::from(slots_per_historical_root);
         state_b.slot = Slot::from(slots_per_historical_root * 2);
 
-        let mut hashes = (0..).into_iter().map(|i| Hash256::from(i));
+        let mut hashes = (0..).into_iter().map(|i| Hash256::from_low_u64_be(i));
 
         for slot in 0..slots_per_historical_root {
             state_a
@@ -404,8 +404,8 @@ mod test {
                 .expect(&format!("should set state_b slot {}", slot));
         }
 
-        let state_a_root = Hash256::from(slots_per_historical_root as u64);
-        let state_b_root = Hash256::from(slots_per_historical_root as u64 * 2);
+        let state_a_root = Hash256::from_low_u64_be(slots_per_historical_root as u64);
+        let state_b_root = Hash256::from_low_u64_be(slots_per_historical_root as u64 * 2);
 
         store.put(&state_a_root, &state_a).unwrap();
         store.put(&state_b_root, &state_b).unwrap();
@@ -429,7 +429,12 @@ mod test {
 
             assert_eq!(slot, i as u64, "slot mismatch at {}: {} vs {}", i, slot, i);
 
-            assert_eq!(hash, Hash256::from(i as u64), "hash mismatch at {}", i);
+            assert_eq!(
+                hash,
+                Hash256::from_low_u64_be(i as u64),
+                "hash mismatch at {}",
+                i
+            );
         }
     }
 }
diff --git a/eth2/types/Cargo.toml b/eth2/types/Cargo.toml
index ae707bc2c..2e4474499 100644
--- a/eth2/types/Cargo.toml
+++ b/eth2/types/Cargo.toml
@@ -12,7 +12,7 @@ compare_fields_derive = { path = "../utils/compare_fields_derive" }
 dirs = "1.0"
 derivative = "1.0"
 eth2_interop_keypairs = { path = "../utils/eth2_interop_keypairs" }
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 hashing = { path = "../utils/hashing" }
 hex = "0.3"
 int_to_bytes = { path = "../utils/int_to_bytes" }
diff --git a/eth2/types/src/beacon_state/committee_cache/tests.rs b/eth2/types/src/beacon_state/committee_cache/tests.rs
index 0fe2fb8a4..28e9d92f8 100644
--- a/eth2/types/src/beacon_state/committee_cache/tests.rs
+++ b/eth2/types/src/beacon_state/committee_cache/tests.rs
@@ -74,7 +74,7 @@ fn shuffles_for_the_right_epoch() {
 
     let distinct_hashes: Vec<Hash256> = (0..MinimalEthSpec::epochs_per_historical_vector())
         .into_iter()
-        .map(|i| Hash256::from(i as u64))
+        .map(|i| Hash256::from_low_u64_be(i as u64))
         .collect();
 
     state.randao_mixes = FixedVector::from(distinct_hashes);
diff --git a/eth2/types/src/beacon_state/tests.rs b/eth2/types/src/beacon_state/tests.rs
index cff034e56..e4c493f92 100644
--- a/eth2/types/src/beacon_state/tests.rs
+++ b/eth2/types/src/beacon_state/tests.rs
@@ -308,7 +308,7 @@ mod committees {
 
         let distinct_hashes: Vec<Hash256> = (0..T::epochs_per_historical_vector())
             .into_iter()
-            .map(|i| Hash256::from(i as u64))
+            .map(|i| Hash256::from_low_u64_be(i as u64))
             .collect();
         state.randao_mixes = FixedVector::from(distinct_hashes);
 
diff --git a/eth2/utils/cached_tree_hash/Cargo.toml b/eth2/utils/cached_tree_hash/Cargo.toml
index c8881eb0f..ce26ee94f 100644
--- a/eth2/utils/cached_tree_hash/Cargo.toml
+++ b/eth2/utils/cached_tree_hash/Cargo.toml
@@ -9,6 +9,6 @@ tree_hash_derive = { path = "../tree_hash_derive" }
 
 [dependencies]
 tree_hash = { path = "../tree_hash" }
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 hashing = { path = "../hashing" }
 int_to_bytes = { path = "../int_to_bytes" }
diff --git a/eth2/utils/merkle_proof/Cargo.toml b/eth2/utils/merkle_proof/Cargo.toml
index b7cd81216..7464773a5 100644
--- a/eth2/utils/merkle_proof/Cargo.toml
+++ b/eth2/utils/merkle_proof/Cargo.toml
@@ -5,5 +5,5 @@ authors = ["Michael Sproul <michael@sigmaprime.io>"]
 edition = "2018"
 
 [dependencies]
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 hashing = { path = "../hashing" }
diff --git a/eth2/utils/ssz/Cargo.toml b/eth2/utils/ssz/Cargo.toml
index 78e65a977..ff5df162d 100644
--- a/eth2/utils/ssz/Cargo.toml
+++ b/eth2/utils/ssz/Cargo.toml
@@ -13,4 +13,4 @@ name = "ssz"
 eth2_ssz_derive = "0.1.0"
 
 [dependencies]
-ethereum-types = "0.5"
+ethereum-types = "0.6"
diff --git a/eth2/utils/ssz/fuzz/Cargo.toml b/eth2/utils/ssz/fuzz/Cargo.toml
index 71628e858..3c922bac9 100644
--- a/eth2/utils/ssz/fuzz/Cargo.toml
+++ b/eth2/utils/ssz/fuzz/Cargo.toml
@@ -9,7 +9,7 @@ publish = false
 cargo-fuzz = true
 
 [dependencies]
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 
 [dependencies.ssz]
 path = ".."
diff --git a/eth2/utils/swap_or_not_shuffle/Cargo.toml b/eth2/utils/swap_or_not_shuffle/Cargo.toml
index 19d5444fb..764dbf409 100644
--- a/eth2/utils/swap_or_not_shuffle/Cargo.toml
+++ b/eth2/utils/swap_or_not_shuffle/Cargo.toml
@@ -12,7 +12,7 @@ harness = false
 criterion = "0.2"
 yaml-rust = "0.4.2"
 hex = "0.3"
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 
 [dependencies]
 hashing = { path = "../hashing" }
diff --git a/eth2/utils/tree_hash/Cargo.toml b/eth2/utils/tree_hash/Cargo.toml
index 3019c2ad0..d69a75faa 100644
--- a/eth2/utils/tree_hash/Cargo.toml
+++ b/eth2/utils/tree_hash/Cargo.toml
@@ -15,7 +15,7 @@ tree_hash_derive = { path = "../tree_hash_derive" }
 types = { path = "../../types" }
 
 [dependencies]
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 hashing = { path = "../hashing" }
 int_to_bytes = { path = "../int_to_bytes" }
 lazy_static = "0.1"
diff --git a/tests/ef_tests/Cargo.toml b/tests/ef_tests/Cargo.toml
index 90f66f355..507e0f7c3 100644
--- a/tests/ef_tests/Cargo.toml
+++ b/tests/ef_tests/Cargo.toml
@@ -10,7 +10,7 @@ fake_crypto = ["bls/fake_crypto"]
 [dependencies]
 bls = { path = "../../eth2/utils/bls" }
 compare_fields = { path = "../../eth2/utils/compare_fields" }
-ethereum-types = "0.5"
+ethereum-types = "0.6"
 hex = "0.3"
 rayon = "1.0"
 serde = "1.0"