diff --git a/beacon-chain/p2p/BUILD.bazel b/beacon-chain/p2p/BUILD.bazel
index 28d92e3b6..af7562399 100644
--- a/beacon-chain/p2p/BUILD.bazel
+++ b/beacon-chain/p2p/BUILD.bazel
@@ -94,6 +94,7 @@ go_library(
         "@com_github_libp2p_go_libp2p_mplex//:go_default_library",
         "@com_github_libp2p_go_libp2p_pubsub//:go_default_library",
         "@com_github_libp2p_go_libp2p_pubsub//pb:go_default_library",
+        "@com_github_libp2p_go_mplex//:go_default_library",
         "@com_github_multiformats_go_multiaddr//:go_default_library",
         "@com_github_multiformats_go_multiaddr//net:go_default_library",
         "@com_github_pkg_errors//:go_default_library",
diff --git a/beacon-chain/p2p/options.go b/beacon-chain/p2p/options.go
index bf5322137..5d4b8fa31 100644
--- a/beacon-chain/p2p/options.go
+++ b/beacon-chain/p2p/options.go
@@ -4,6 +4,7 @@ import (
 	"crypto/ecdsa"
 	"fmt"
 	"net"
+	"time"
 
 	"github.com/libp2p/go-libp2p"
 	mplex "github.com/libp2p/go-libp2p-mplex"
@@ -11,6 +12,7 @@ import (
 	"github.com/libp2p/go-libp2p/core/peer"
 	"github.com/libp2p/go-libp2p/p2p/security/noise"
 	"github.com/libp2p/go-libp2p/p2p/transport/tcp"
+	gomplex "github.com/libp2p/go-mplex"
 	ma "github.com/multiformats/go-multiaddr"
 	"github.com/pkg/errors"
 	"github.com/prysmaticlabs/prysm/v5/config/features"
@@ -135,3 +137,8 @@ func privKeyOption(privkey *ecdsa.PrivateKey) libp2p.Option {
 		return cfg.Apply(libp2p.Identity(ifaceKey))
 	}
 }
+
+// Configures stream timeouts on mplex.
+func configureMplex() {
+	gomplex.ResetStreamTimeout = 5 * time.Second
+}
diff --git a/beacon-chain/p2p/service.go b/beacon-chain/p2p/service.go
index a70ede6db..f87a99aa1 100644
--- a/beacon-chain/p2p/service.go
+++ b/beacon-chain/p2p/service.go
@@ -124,7 +124,8 @@ func NewService(ctx context.Context, cfg *Config) (*Service, error) {
 	if err != nil {
 		return nil, errors.Wrapf(err, "failed to build p2p options")
 	}
-
+	// Sets mplex timeouts
+	configureMplex()
 	h, err := libp2p.New(opts...)
 	if err != nil {
 		log.WithError(err).Error("Failed to create p2p host")